Science Researcher Update

Metabolic Determinants of Stem Cell Pluripotency and Cell Fate Commitments

Written by BCI Staff | Dec 24, 2012 7:06:00 AM

Metabolic Determinants of Stem Cell Pluripotency and Cell Fate Commitments

Symposium - New York City, United States

The metabolic needs of cells are determined by function and fate. Pluripotent cells must make the choice to either self-renew, or commit to alternative cell fates. What are the changes in metabolic programs and cell bioenergetics associated with this stem cell choice? Do cell fate decisions determine metabolic activity, or do metabolic switches trigger the commitment to alternative cell fates? How do rapidly proliferating cells signal their comprehensive needs for more ATP, reducing equivalents, and biosynthetic intermediates that provide for growth and division? Can small molecules be used to divert stem cells toward expansion of desired lineages for cell-based therapies? Speakers at this symposium will present their latest metabolomic findings on stem cell metabolism vs. lineage commitment — and how this knowledge may be applied for future therapies.

(Courtesy of the New York Academy of Sciences, via backreaction.blogspot.com)

Metabolic Determinants of Stem Cell Pluripotency and Cell Fate Commitments

Fri, Feb 01, 2013

New York Academy of Sciences

250 Greenwich Street, 40th Floor, New York City, United States

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