Conference - Heidelberg, Germany
At its most fundamental level, this breakthrough in resolution is based on the fact that tiny features in the sample are no longer discerned by the phenomenon of focusing. Rather the feature molecules or molecular tags are prompted to briefly assume two different states (e.g. fluorescence on/off) so that they become distinguishable when illuminated by the same diffraction pattern.
Thus, in modern superresolution microscopy, fluorescent molecular tags have to fulfill a double role. Not only do they have to highlight the features of interest, but they also have to provide the (pair of) states required for separation. Therefore, it is the symbiosis of molecular tags and optical design that makes the microscopes of today sharp and bright.
This conference brings together experts in fluorescence and labeling with those designing and applying new concepts of far-field optical nanoscopy.
Organization: German Cancer Research Center
Wed, Sep 24, 2014 - Fri, Sep 26, 2014
German Cancer Research Center
Im Neuenheimer Feld 280, Heidelberg, Germany