Science Researcher Update

Stalked Alpha-Proteobacteria and Relatives: From Genes to Structure

Written by BCI Staff | Feb 4, 2014 8:46:00 PM

Stalked Alpha-Proteobacteria and Relatives: From Genes to Structure

Workshop - Ebsdorfergrund, Germany

The stalked alpha-Proteobacteria and their cousins occupy an underappreciated, yet central and unprecedented position in fundamental and translational research. Long recognized as one of the prime model systems to elucidate important concepts in cellular and developmental biology, including the mechanisms underlying cell polarity, morphogenesis, asymmetric division and cell-cycle control, the stalked alphaproteobacteria were recently used to illuminate cell budding, adhesion, subcellular compartmentalization and to design surface–anchored antibody-display vehicles for biotechnological applications. The core regulatory circuitry for these functions is conserved amongst alphaproteobacteria and compelling evidence surfaced indicating that this circuitry also orchestrates symbiosis (Rhizobiaceae) and/or virulence (Brucellaceae, Bartonellaceae, Rickettsiaceae, Agrobacteria) and possibly other functions in related bacteria. The topics covered at the workshop include:

Cell cycle coordination and regulation

Morphogenesis and polarity

Cytokinesis and cell wall growth

Adhesion and secretion

Virulence and symbiosis

Evolution and modeling

Organization: EMBO

(Courtesy of Stalked Alpha-Proteobacteria, via boundless.com)

Stalked Alpha-Proteobacteria and Relatives: From Genes to Structure

Sun, Mar 30, 2014 - Thu, Apr 03, 2014

Rauischholzhausen, Ebsdorfergrund, Germany

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