Science Market Update

Increasing Efficiency By Killing Lazy Cells at Washington University

Posted by Sam Asher on Thu, Mar 24, 2016

Chemical bioengineers find and create bacteria for several different purposes, such as eating chlorine and consuming toxic byproducts of biodiesel plants. A closer look at these bacterial communities undertaken in a study at Washington University in St. Louis shows that there is actually a division of labor between bacterial workers and layabouts.

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Tags: WashU, BioResearch Product Faire Event, MO, St Louis, Washington Univsersity St. Louis, 2016

WUSTL Receives $60M to Research the Genetics of Common Diseases

Posted by Laura Braden on Fri, Feb 19, 2016

The National Institutes of Health (NIH) recently launched a new network of institutions - called the Centers for Common Disease Genomics (CCDG) - which will study common conditions such as heart disease, stroke, diabetes, and autism to see how genetics and DNA contribute to the risk of these diseases. The McDonnell Genome Institute at Washington University in St. Louis is one of four institutions involved in this network and will be receiving $60 million over the next four years to study genomics and common diseases.    

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Tags: Washington University St. Louis, Midwest, Missouri, WashU, heart disease, Diabetes, Autism, BioResearch Product Faire Event, MO, St Louis, NIH funding, 2016, Centers for Common Disease Genomics, stroke, CCDG

WUSTL Chemist Introduces Targeted Antibiotic In Response to Iraqi Superbug

Posted by Sam Asher on Thu, Jan 28, 2016

For years, we’ve been discussing reasons not to use antibiotics and have seen the development of new alternatives, such as spray-on antibodies and internal bacterial combustion. Despite this, antibiotics continue to be widely used today. Scientists at Washington University in St. Louis theorize that antibiotics are here to stay, but perhaps it is the definition of antibiotics that needs to be changed.

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Tags: Washington University St. Louis, WashU, BioResearch Product Faire Event, MO, St Louis, 2016

$13.7M Awarded to St. Louis Researchers to Develop Multiple Myeloma Treatments

Posted by Laura Braden on Tue, Jan 12, 2016

Multiple myeloma is a rare form of cancer that affects the immune system in about 0.7% of Americans. According to the American Cancer Society, approximately 26,850 new cases were expected to be diagnosed in 2015, and 11,240 deaths were expected to occur. Although there are treatments available to fight this cancer, patients frequently relapse, demonstrating the need for new treatments.

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Tags: Washington University St. Louis, Midwest, WashU, St. Louis Bioresearch Product Faire Event, cancer research, Cancer Treatment, MO, St Louis, new funding, 2016, BioResearch Product Faire, Multiple Myeloma

WUSTL Opens New Regenerative Medicine Research Center

Posted by Laura Braden on Tue, Dec 29, 2015

Life science research institutions around the country are constantly expanding and providing more space and opportunity for researchers to conduct their work. Recently, Baylor St. Luke's at the Texas Medical Center announced the construction of a new medical campus that was underway and UGA opened a new Veterinary Research Center earlier this year. Washington University in St. Louis is also expanding research space, with a newly opened Center for Regenerative Medicine.

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Tags: Midwest, Washington University, WashU, Regenerative Medicine, MO, St Louis, New research center, 2016, BioResearch Product Faire

WUSTL Team Unlocks Immune Potential

Posted by Sam Asher on Thu, Oct 22, 2015

Our immune system is our best defense against sickness on a day-to-day basis, and bioresearchers have been trying to ramp it up to handle bigger threats for some time now. A research lab from MSU found that fish oil can significantly boost immune activity, and a UCSF team discovered genetic “enhancers” that help prevent autoimmune diseases. At the Washington University in St. Louis, scientists are finding that our immune system has the potential to be much stronger and are discovering how to tap into that potential.

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Tags: Washington University St. Louis, WashU, 2015, BioResearch Product Faire Event, MO, St Louis

WUSTL Researchers Lower Blood Sugar Without Insulin

Posted by Sam Asher on Thu, Sep 10, 2015

A rational approach to tackling diabetes using life science research is to focus on insulin. We’ve seen a research team at Emory University transplant insulin-producing cells, and we’ve reported on an Urbana-Champaign team trying to release insulin in patients’ cells. Now researchers at Washington University at St. Louis are taking a new approach by directly reducing blood sugar without the use of insulin.

Brian Finck (image left, courtesy WUSTL) believes that rather than rely on insulin to lower blood sugar in patients with diabetes, it’s easier to cut out the middle man and reduce glucose levels using genetics. He and fellow WUSTL professor Kyle McCommis found that shutting down a particular liver protein dramatically reduced glucose production in the liver.

“We think this strategy could lead to more effective drugs for type 2 diabetes,” says Finck, who is an associate professor of medicine in the Division of Geriatrics and Nutritional Science. “A drug that shuts down glucose production has the potential to help millions of people affected by the most common form of diabetes.”

 

(Brian N. Finck, PhD (left), and Kyle S. McCommis, PhD analyze blood sugar levels to evaluate their new strategy. Image courtesy WUSTL)

The team has already initiated clinical trials using the drug compound MSDC-0602. So far, the drugs have been successful in inhibiting the protein and reducing blood sugar levels. Dr. Finck is working with the biopharmaceutical company Metabolic Solutions Development Co. to facilitate production of the drug.

Funding for this research came from the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health as well as the Foundation for Barnes-Jewish Hospital and the Robert A.Welch Foundation. For additional information about funding for research at Washington University in St. Louis, read our free WUSTL Funding Statistics Report, available via the link below:

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Tags: WashU, Washington University in St. Louis, 2015, BioResearch Product Faire Event, MO, St Louis

Designing More Efficient Photosynthesis at WUSTL

Posted by Sam Asher on Thu, Aug 06, 2015

One of the most pressing pursuits in bioscience is increasing agricultural production. The Food and Agriculture Organization estimates that, as a planet, we need to produce 70 percent more food by the year 2050 in order to keep up with increasing population. We have already shone our spotlight on several university research teams who are tackling this problem, like the UW team attempting to increase flowering rates and the UIUC team who spliced algae genes to increase photosynthesis. Now we look to Washington University in St. Louis for some novel ideas about optimizing photosynthesis.

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Tags: WashU, Washington University in St. Louis, 2015, BioResearch Product Faire Event, MO, St Louis

WUSTL Team Blocks Brain Tumor Regeneration

Posted by Sam Asher on Thu, Jun 18, 2015

Destroying a tumor is sometimes only the beginning when it comes to fighting cancer. We’ve seen a UCLA team eradicate tumor remnants in the bloodstream and a Cincinnati researcher who developed a method to prevent breast cancer tumors from leaving behind stem cells from which they could regenerate. Now a team at Washington University in St. Louis has discovered a way to shut down the stem cells in the tumors of brain cancer.

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Tags: WashU, 2015, BioResearch Product Faire Event, MO, St Louis, Washington Univsersity St. Louis

WUSTL Team Finds Potential Treatment for Fragile X Carriers

Posted by Sam Asher on Thu, May 07, 2015

For some diseases, one can “carry” the disease without showing any of its symptoms. In the case of Fragile X syndrome, a cause of autism and intellectual disability, there’s no such concept. However, researchers at Washington University at St. Louis are working on a way to reduce these carrier symptoms.

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Tags: WashU, 2015, BioResearch Product Faire Event, MO, St Louis, Washington Univsersity St. Louis

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