If you have ever had a severe headache, you may have noticed how pain takes a toll on your emotional state, especially if you have ever experienced a migraine. Taking pain medication can help with how a headache feels physically, but what effects does pain relief have on people emotionally? Believe it or not, a number of studies have been conducted on how pain medication like ibuprofen can ameliorate emotional pain. Research has proven that ibuprofen can indeed relieve emotional stress, but scientists at the University of Texas, Austin have recently discovered that it is much more effective on women than on men. Men who take the drug say that they experience harsher feelings of rejection, while women report feeling better.