Science Market Update

UAB Researchers Make Breakthroughs in Parkinson's Treatments

Posted by Rebecca Partridge on Wed, Aug 03, 2016

Parkinson’s is a degenerative condition that affects over one million Americans  - even greater than the number of those suffering from multiple sclerosis, muscular dystrophy and Lou Gehrig's disease combined.  There is no cure, but this month researchers at the University of Alabama at Birmingham made two important breakthroughs for treating the disease.  One group of researchers has discovered the cause of the negative side-effects of L-DOPA and a potential way to counter-act it.  Another group of researchers have “discovered an interaction in neurons that contributes to Parkinson’s Disease and they have shown that drugs now under development may block the process.”   

(Image of the University of Alabama, Birmingham courtesy of Jaymay via Wikimedia Commons)

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Tags: Parkinson's Disease Research, University of Alabama Birmingham, University of Alabama at Birmingham, Parkinson's Disease, biomedical researh, Dr. Volpicelli-Daley, Dr. Standaert

$29M Core Grant Awarded to Alabama for Cancer Research Center

Posted by Rebecca Partridge on Wed, Jun 29, 2016

(Image courtesy of Wikimedia commons)

University of Alabama at Birmingham received a $29 million grant from the National Cancer Institute. This five year core grant will support six research programs at the UAB Comprehensive Cancer Center. The renewal of the Cancer Center Support Grant, the most prestigious federal grant that a cancer research and treatment program can earn, also extends UAB’s elite “comprehensive” designation. According to the UAB News website this designation is awarded for scientific excellence and the ability to integrate diverse research approaches in the fight against cancer.

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Tags: Bioresearch funding, cancer research, Alabama, University of Alabama, Cancer Treatment, Cancer, University of Alabama Birmingham, UAlab, UAB, University of Alabama at Birmingham, Cancer Center, cancer researchers, fight cancer, 2016, cancer reserach, Bioresearch Grant, Comprehensive Cancer Center

Research at UAB Leads to Potential New Treatment for Parkinson’s

Posted by Rebecca Partridge on Mon, Jun 06, 2016

(1886 Sketch of Person with Parkinson's by Sir William Richard Gowers Courtesy of Wikimedia Commons)

Researchers at the University of Alabama, Birmingham have discovered a potential new approach to reducing the damage done by Parkinson's disease. They found that suppressing a key cell-signaling pathway in the brain lessened the destructive inflammation and nerve degradation in the area of the brain affected by Parkinson’s. In the study, rats were used to model the disease by inducing an overexpression of a-synuclein, a protein that is abundant in the human brain. The accumulation of α-synuclein is a core feature of Parkinson’s disease. This accumulation leads to the activation of the brain's immune cells and the production of inflammatory signaling chemicals, which leads to neurodegradation. The rats that were then given a JAK/STAT pathway inhibitors (known as Jakinibs) did not have the immune response, the inflammatory activation, or the neurodegeneration that those that did not receive the inhibitor experienced.    

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Tags: Parkinson's Disease Research, Alabama, University of Alabama, University of Alabama Birmingham, UAlab, Birmingham, AL, University of Alabama at Birmingham, 2016, Parkinson's Disease

NICHD Funds University of Alabama's Zika Virus Study

Posted by Rebecca Partridge on Fri, May 06, 2016

Microcephaly has been linked to the Zika virus

(Photo courtesy of of wikimedia commons)  

With Zika outbreaks in Mexico, Central America, and South America, the National Institute of Child Health and Human Development (NICHD) is attempting to stop the virus at our border. To assist with this effort, the institute is funding a study led by Dr. William Britt, Professor of Pediatric Infectious Diseases at the University of Alabama at Birmingham (UAB). This study will take place in Brazil, where the World Health Organization (WHO) estimates that between 500,000 and 1.5 million people have been infected by Zika. The study will follow pregnant women in Brazil regardless of their Zika virus infection status and follow the infants suspected of having Zika from birth until 2 years of age.

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Tags: Bioresearch, University of Alabama, South, University of Alabama Birmingham, UAlab, UAB, Birmingham, AL, BioResearch Product Faire, microcephaly, zika, Dr. Britt

Life Science Grant Worth $8.1M Awarded to University of Alabama

Posted by Jennifer Nieuwkerk on Fri, Jul 18, 2014

Researchers at the University of Alabama recently received $8.1 million in life science funding from the National Institutes of Health for a study involving the etiology of geographic and racial differences in stroke. The life science grant was awarded in January of 2014 by the National Institute of Neurological Disorders and Stroke, a branch within the National Institutes of Health.

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Tags: 2014, new research funding, Alabama, University of Alabama, University of Alabama Birmingham, BioResearch Product Faire Event, UAlab, Birmingham, AL, new grant

University of Alabama is an Unexpected Standout for Lab Suppliers

Posted by BCI Staff on Tue, Oct 09, 2012

The University of Alabama is an unexpected standout in the science research marketplace.  This campus ranks among the top in the nation, flanking closely with the top NIH funded universities, and yet there is surprisingly little sales rep traffic on campus.

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Tags: Southeast, 2012, Alabama, University of Alabama, University of Alabama Birmingham, BioResearch Product Faire Event, UAB, Birmingham, AL, advertising, event program advertising, ads, branding

University of Alabama Wins $7 Million Research Grant

Posted by Jennifer Nieuwkerk on Thu, Jul 12, 2012

The University of Alabama at Birmingham has been awarded a $7 million research grant to continue its leadership in pioneering clinical trials in the treatment of neurofibromatosis 1 and 2 and schwannomatosis, all rare genetic diseases. According to the Birmingham Business Journal, the circumstances of these diseases lead to non-cancerous tumors forming on the nerves and potentially causing blindness, hearing loss, learning disabilities, pain or deformity.

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Tags: 2012, Alabama, University of Alabama, University of Alabama Birmingham, BioResearch Product Faire Event, UAB, Birmingham, AL, research grant

University of Alabama to Profit from Research & Development Tax Incentive

Posted by Jaimee Saliba on Wed, Mar 28, 2012

One of the ways to encourage companies to invest in research is to offer them a tax credit incentive, and that's exactly what many states do, including, soon, Alabama.  If the company does their own research, they get one tax break, but if they have it done by a public research institution like the University of Alabama, they get a much larger break: 15% under Alabama's proposed new law. That's good news for UAB, UAT, and other major research campuses in the state. And the rate may be even higher if Alabama tries to match North Carolina's incentive, which just went up to 20%.

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Tags: New research facilities, Alabama, University of Alabama Birmingham, BioResearch Product Faire Event, Funding, Birmingham, Southern Region

New Cardiovascular Research Center to Grow UAB Funding, Faculty, & Labs

Posted by Jaimee Saliba on Tue, Feb 14, 2012

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Tags: Biomedical expansion, cardiovascular research, Alabama, University of Alabama Birmingham, Southern Region

UAB Cancer Center Wins $2.3M SPORE Award for Brain Tumor Research

Posted by BCI Staff on Tue, Nov 15, 2011

The University of Alabama in Birmingham runs one of an elite group of Comprehensive Cancer Centers in the United States, as designated by the National Cancer Institute (NCI).  The NCI's Translational Research Program is in charge of administering SPORE awards, which are focused on specific organ sites.  Now UAB is also a SPORE grantee for its brain tumor program, thanks to a recent $2.3M award over three years to its Cancer Center in conjunction with the UAB Division of Neurosurgery. UAB is one of only four institutions to receive a brain-tumor SPORE grant.

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Tags: cancer research, Southeast, Alabama, University of Alabama Birmingham

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