Science Market Update

UAB Researchers Make Breakthroughs in Parkinson's Treatments

Posted by Rebecca Partridge on Wed, Aug 03, 2016

Parkinson’s is a degenerative condition that affects over one million Americans  - even greater than the number of those suffering from multiple sclerosis, muscular dystrophy and Lou Gehrig's disease combined.  There is no cure, but this month researchers at the University of Alabama at Birmingham made two important breakthroughs for treating the disease.  One group of researchers has discovered the cause of the negative side-effects of L-DOPA and a potential way to counter-act it.  Another group of researchers have “discovered an interaction in neurons that contributes to Parkinson’s Disease and they have shown that drugs now under development may block the process.”   

(Image of the University of Alabama, Birmingham courtesy of Jaymay via Wikimedia Commons)

Read More

Tags: Parkinson's Disease Research, University of Alabama Birmingham, University of Alabama at Birmingham, Parkinson's Disease, biomedical researh, Dr. Volpicelli-Daley, Dr. Standaert

Research at UAB Leads to Potential New Treatment for Parkinson’s

Posted by Rebecca Partridge on Mon, Jun 06, 2016

(1886 Sketch of Person with Parkinson's by Sir William Richard Gowers Courtesy of Wikimedia Commons)

Researchers at the University of Alabama, Birmingham have discovered a potential new approach to reducing the damage done by Parkinson's disease. They found that suppressing a key cell-signaling pathway in the brain lessened the destructive inflammation and nerve degradation in the area of the brain affected by Parkinson’s. In the study, rats were used to model the disease by inducing an overexpression of a-synuclein, a protein that is abundant in the human brain. The accumulation of α-synuclein is a core feature of Parkinson’s disease. This accumulation leads to the activation of the brain's immune cells and the production of inflammatory signaling chemicals, which leads to neurodegradation. The rats that were then given a JAK/STAT pathway inhibitors (known as Jakinibs) did not have the immune response, the inflammatory activation, or the neurodegeneration that those that did not receive the inhibitor experienced.    

Read More

Tags: Parkinson's Disease Research, Alabama, University of Alabama, University of Alabama Birmingham, UAlab, Birmingham, AL, University of Alabama at Birmingham, 2016, Parkinson's Disease

UPitt Researchers Use Gene Therapy to Treat Parkinson's Disease

Posted by Katheryn Rein on Tue, Apr 12, 2016

A new strategy for combating the neurologically destructive effects of Parkinson's Disease has been developed jointly by researchers at the University of Pittsburgh and the University of Pittsburgh School of Medicine. 

Read More

Tags: University of Pittsburgh, Parkinson's Disease Research, gene therapy, UPITT, PA, Pittsburgh, Parkinson's Disease

Test for Parkinson’s on the Horizon Due to Fox-Funded Research at UC San Diego

Posted by Rebecca Partridge on Fri, Mar 11, 2016


For the 60 thousand Americans diagnosed with Parkinson's Disease each year, the challenges are huge. From the shuffling gait, hunched posture, and tremors to the declining cognitive functions, nearly every aspect of the activities of daily living are impacted. But perhaps the the largest challenge is receiving an accurate diagnosis in the first place.

Read More

Tags: CA, University of California San Diego, California, Biomarkers, San Diego, UCSD research, UCSD, UC San Diego, Parkinson's Disease, Dr. Paula Desplats, Michael J. Fox Foundation, biosciences, West Coast

Philadelphia Researchers Produce GM1 Ganglioside to Treat Parkinson's

Posted by Laura Braden on Tue, Jan 05, 2016

Parkinson's Disease is a devastating neurodegenerative disease that affects people's motor functions. As of today, there are no cures for Parkinson's Disease, and treatments are only able to alleviate symptoms. Researchers across the nation are heavily studying the disease, with the goal of learning more about the onset and progress of the disease to help scientists develop treatment methods.

Read More

Tags: Northeast, Thomas Jefferson University, Parkinson's Disease Research, Philadelphia, PA, ThomJeff, 2016, Parkinson's Disease, BioResearch Product Faire, GM1 ganglioside

Connect With Us   Like Us on Facebook   Follow Us on Twitter   See our latest photos!   Join Us on Google +   Find Us on LinkedIn   Pin our latest stories!

Subscribe to Company News

Subscribe to this blog!