Duke received a $28 Million grant from the NIH to discover immunologic research directed at tackling major scientific problems that hinder the development of an effective HIV-1 vaccine. The vaccine strategy will be based on identifying and targeting novel HIV-1 vulnerabilities to B, T and NK cell immune responses and then using this information to design vaccines that will induce protective immunity at the time and location of HIV-1 transmission.Read More
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According to the NIH, "Genomic medicine is an emerging medical discipline that involves using genomic information about an individual as part of their clinical care (e.g. for diagnostic or therapeutic decision-making) and the health outcomes and policy implications of that clinical use."
In 2018, Duke University was awarded six grants from the National Human Genome Research Institute, a part of the NIH. Two of the grants will total about $9 million over the next 5 years. The first grant establishes the Duke Center for Applied Genomics & Precision Medicine. The second supports a Duke initiative to gather the family medical histories of low-income patients and assess their inherited risk of certain diseases.
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Each year, Duke's Department of Medicine receives more than $130 million in federal research grants to fund basic, clinical, and transnational research. For the fiscal year 2015-2016 Duke University also received over $180 in private donations from individuals and various foundations to support their lifesaving research. An example of their success is a recent study conducted by Duke University researchers that may save patients with atrial fibrillation (A-fib) from suffering from strokes.
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Antibodies are essential for keeping the body healthy, as they are produced in the immune system and sent to fight harmful substances. Since they are essential for fighting off unwanted antigens in the body, antibodies are a hot topic that researchers are constantly studying. Recently, a research team from Duke University developed an antibody that specifically targets cancer cells, providing a possible new immunotherapy for cancer. (Image of antibody-antigen complex courtesy of Alejandro Porto via Wikimedia Commons)Read More
Researchers at Duke University in Durham, North Carolina have been studying how cells regenerate skin tissue through the use of genetically engineered, technicolor zebrafish.Read More
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According to the Center for Disease Control, an estimated 198 million cases of malaria occurred worldwide and 500,000 people died, mostly children in the African Region.Read More
By combining time-lapse luminescence microscopy with a microfluidic device, researchers at Duke University were able to track the dynamics of cell cycle genes in single yeast with subminute exposure times over many generations. Typically time-lapse fluorescence microscopy of genetically encoded fluorescent proteins is the gold standard for measuring in vivo dynamics of gene expression in single cells.Read More