Researchers at Stony Brook University in collaboration with colleagues at Johns Hopkins School of Medicine used DNA sequencing methods to make a new discovery: the direct causation of exposure to aristolochic acid (AA), which is found in a plant that’s been used in herbal remedies for thousands of years, in the development of urothelial cancer.
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The summer of 2012 is set to go down as one of the driest and worst years for US farmers, but it's proving to be an excellent season for fruit science, especially at the University of Arizona, Tucson. In June we saw the sequencing of the tomato genome (technically a fruit), which was a breakthrough in genetics research. The Arizona Genomics Institute has now cracked another complex code: the genome of the banana.
Tags: Southwest, Arizona, University of Arizona, University of Arizona Tucson Research, DNA Sequencing, genomic research, biology research, 2012, AZ, DNA Research, genomics research, genome research, Genetics, banana, Front Line event, Tucson, UA
Remember the character of Pigpen in the comic strip Peanuts? He walked around within a cloud of dust and dirt. Well, according to University of California Davis microbiologist Jonathan Eisen, we all live within our own aura of microbes --10 times as many microbial cells as human cells!--and that's probably a very good thing for our health. It sounds counterintuitive at first, but not all microbes are bad. We've come to realize intestinal biota are good for digestion and colon health (among other things), but the outside of our bodies is also host to vast colonies of microbes that are increasingly proving to be vital cohorts of our immune system.
Last year in a blog of ours on the future of genome sequencing we referenced a July appeals court ruling that protected Utah's Myriad Genetics' patent on two genes known to be indicators of breast cancer risk. Now, in a recent Supreme Court ruling on that same case, the previous ruling has been overturned and the case returned to the lower court for rehearing. This decision follows another important high court ruling on the patentability of genes: Mayo vs. Prometheus Labs (San Diego), which also just ruled against a company's right to hold patents on human genes, and which was quoted as a precedent in the latest Myriad judgement.
Michael E. Zwick is a geneticist at Emory University School of Medicine in Atlanta, and his recently published study in October's Genomics journal on Identifying Autism Susceptibility Genes explores a new PCR technology for rapid, targeted, and highly accurate sequencing and identification of novel genetic variants affecting X chromosome genes. Autism is four times more common in men, who possess only one copy of the X chromosome, and Zwick's research explores this possible correlation.