Glioblastoma is the most aggressive form of brain cancer, and like many other cancers, its causes are still unknown. Since it is generally very malignant, researchers know that glioblastoma cells frequently reproduce to keep the tumor alive and help it grow, and the location of glioblastoma in the brain provides the cells with ample blood supply. Through their study of glioblastomas, researchers at Columbia University Medical Center recently discovered that the gene KLHL9 is a leading factor in the cause of glioblastomas.Read More
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Columbia University’s medical school is undergoing a groundbreaking transformation in the most literal sense of the word: Construction crews have broken ground on one of two new medical buildings in the works at the powerhouse university’s campus. The new buildings will include teaching space as well as state-of-the-art science research labs.
Research lab scientists at Columbia University received $6.3 million in life science research funding this spring for Columbia’s Center for Research in Diagnostics and Discovery. The research grant was awarded by the administering institute the National Institute of Allergy and Infectious Diseases. The department of Public Health and Preventative Medicine within the Schools of Public Health at Columbia University will use the research funding to advance detection of certain diseases and predict how effective specific therapies can be in prevention and treatment. The Project Information page on the NIH website goes into further detail:
Three researchers at Columbia University recently received NIH awards ranging from $1.9 million to $4 million in life science funding over the next five years. The prizes, part of the Health High Risk-High Reward program, were awarded to researchers whose work suggests highly original approaches to major challenges in biomedical research. The winners are Rafael Yuste, Ozgur Sahin, and Christine Ann Denny.
Columbia University Medical Center administrators recently broke ground at a new medical facility, which will be called the Medical and Graduate Education Building. Columbia University is planning on completing the new medical facility by 2016. Located on Haven Avenue between 171st and 172nd streets in Washington Heights, the building is expected to help resolve the medical center’s space shortages. Architecture firms Diller Scofidio + Renfro and Genseler designed the building, which is described as modern and includes floor-to-ceiling glass windows and a terrace on top of the building with great views of the Hudson River.
Researchers at Columbia University Medical Center recently conducted a study examining brains of a number of different ages donated by people who died without signs of neurologic disease. During the course of the investigation, researchers came to the conclusion that a certain hippocampus gene’s function deteriorates in older people. The researchers believe that age-related memory loss is distinct condition from Alzheimer’s or pre-Alzheimer’s, and that the condition may be treatable in the future.
Researchers at Columbia University recently conducted a study aiming to identify an Alzheimer’s gene in African-Americans. The results were published in the April 10 issue of the Journal of the American Medical Association, and the study was funded by NIH research grants. African-Americans with the ABCA7 gene have almost twice the amount of risk of developing late-onset Alzheimer’s disease. According to a Columbia University news article, the gene is involved in producing cholesterol and lipids, and researchers believe that lipid metabolism may be a key pathway in Alzheimer’s disease in African-Americans, more so than it may be in white people.
If significant research is any indication of the quality of lab sales leads at life science marketing events held on Columbia University’s campus, this next story is worth reading about. Columbia University Medical Center researchers conducted a significant study that has identified a number of metabolic expression changes in the gene expression data from 22 tumor types. The analysis also points to hundreds of medications that could remove a tumor’s fuel supply or inhibit a tumor’s synthesis. The study was published in Nature Biotechnology.
A $20 million gift from Philip and Cheryl Milstein to the Columbia University Medical Center was announced recently. The donation will be used as part of an effort to rejuvenate the medical campus with construction of the Medical & Graduate Education Building on Haven Street between West 171st and West 172nd Streets. Administrators at Columbia University Medical Center said the building will include “innovative classroom and study spaces that will incorporate state-of-the-art information technology while facilitating collaborative, team-based learning.” The new building’s function will be the training of students in the College of Physicians and Surgeons and the biomedical science departments in the Graduate School of Arts and Sciences. (Read our earlier blog on this new construction project at CUMC here.)
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