Science Market Update

Harvard Researchers Identify SALL4 Cancer Gene Inhibitor

Posted by Jennifer Nieuwkerk on Mon, Jul 15, 2013

Science researchers at Harvard University have discovered a gene found in the most devastating forms of cancer that controls embryonic stem cell self-renewal. The gene, SALL4, enables stem cells to keep dividing rather than grow into mature cells. The gene is re-expressed in almost all cases of acute myeloid leukemia and between 10 to 30 percent of lung, ovarian, gastric, liver, breast and endometrial cancer. Researchers say they can make a strong case that the gene plays a part in tumor formation. The breakthrough marks the beginning of a search for a drug that can block the gene’s activity.

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Tags: Massachusetts, Harvard, Northeast, Boston, BioResearch Product Faire Event, MA, Harvard University, 2013, Cambridge, 2014

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