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New $10 Million COBRE Grant For UNR Neuroscience Research

  
  
  
  

 

600px Brain chrischan resized 600

(Courtesy of Wikimedia Commons and Christian R. Linder)

Can’t remember where you parked the car? With the help of a new grant at UNR we may all be sleeping and remembering more soon. The University of Nevada, Reno is about to improve with a new $10M Center of Biomedical Research Excellence (COBRE) grant from the National Institute of General Medical Sciences. The grant is designed to help the university improve its faculty and expertise in Integrative Neuroscience. This grant joins two other COBRE grants currently awarded to UNR, the maximum number of grants that any one university can have. In order to receive this award a university must already have made strides toward becoming a leading university in a particular field. For UNR, this field is Integrative Neuroscience. The grant is designed to provide the university with addition funds to hire new faculty researchers, furthering their ability to become a leading research university in a particular field.

"We fully appreciate the importance of developing our capabilities in the field of neuroscience," said University President Marc Johnson. "The investments we make in this program will increase the quality and impact of our institution, opening up new opportunities not only for our students and researchers, but also for northern Nevada. These investments bring resources, technology and economic development opportunities to our community."

 657px MRI Philips resized 600

(Courtesy of Wikimedia Commons and Jan Ainali)

This COBRE grant is only part of the university's plan to expand its neuroscience program. The university plans to hire more professors with research expertise in cognitive neuroscience and MRI technology. UNR intends to spend nearly half a million dollars purchasing two new neuro-imaging systems, as well as creating an on campus MRI facility staffed by a new faculty member.  

At UNR there are currently 5 assistant professors who will benefit from this new funding. The professors are Assistant Professor of Psychology Marian Berryhill, Assistant Professor of Psychology Gideon Caplovitz, Assistant Professor of Biology Alexander van der Linden, Assistant Professor of Biology Alex Keene, and Assistant Professor of Electrical and Biomedical Engineering Xiaoshan Zhu.

marion berryhill Professor Marion Berryhill’s laboratory is exploring how brain lesions affect cognition and memory, techniques to improve human memories, and the nature of internal attention. In her research she uses neuropsychological (patient-based), neuroimaging (MRI) and neurostimulation to understand the inner working of the brain. Her laboratory is currently using electrical stimulation to the brain as a technique to improve mental ability during memory tests. All of these projects are aimed at helping us to understand the nature of memory as well as how to maintain our memory as we age.

Courtesy of Department of Psychology 

 
 Caplovitz  Gideon Caplovitz is interested in understanding how the brain perceives the environment we live in. His laboratory uses a variety to tools such as: psychophysical, eye-tracking, and neuroimaging (fMRI, EEG) to measure the changes in the brain with visual perception. In his work, he tricks the brain into seeing images that do not exist. This technique is only possible in people with no brain damage. In the future, his tests could be uses as a early detection system for brain damage or disfunction.
 Courtesy of Caplovitz lab  
 Alexander van der Linden  Alexander van der Linden's laboratory is studying how environmental changes affect circadian rhythms using the nematode (Caenorhabditis elegans) as a simple animal model. Circadian rhythms are 24-hour cycles that govern how our body functions, and reacts to outside forces like temperature and sunlight. Already the laboratory has identified genes that are a part of the circadian system in nematodes. He hopes to use this research to help stroke patients in the future. According to Professor Linden,“When stroke patients have a brain injury, often their circadian rhythms are disrupted, telling them when to eat and sleep.”
 Courtesy of Alexander van der Lindenlab  
 alex keene resized 600  Professor Alex Keene is studying how our memories are affected by sleep deprivation. In his lab he is using Drosophila fruit fly, an inexpensive, animal model with fast life cycle to find genes that control sleep and memory. With any luck, Professor Keene will help us to sleep better and remember more.
 Courtesy of Department of Biology  
 zhu resized 600  The laboratory of professor Xiaoshan Zhu is developing new nanoparticles that are able to detect extremely low levels of biomarkers, such conditions as: cancer, infectious diseases, and neural diseases. These nanoparticle have a very small volume in comparison to their surface area, and are engineered with unique properties. These properties allow them to target specific humans locations in the human body from proteins to tissue. The presence of these particles lets MRI create clearer picture with more contrast. With the help of these engineered nanoparticles, we will be able to see brain damage and help fix it.
 Courtesy of Integrated Bio-Analytical Systems Lab  

  

With the help of these researchers and their Integrative Neuroscience projects at UNR, we may be able to detect early brain damage, pinpoint the location accurately, restore Circadian Rhythms to stroke vicitms, and keep our memory as we age. So, perhaps in the future with the help of these University of Nevada, Reno scientists, we will more reliably be able to remember where we parked the car.  

To read more of our recent research and grants articles on UNR, here is a link to visit our science market blog:

If your are a life science researcher or laboratory supplier, Biotechnology Calendar, Inc. will be holding its annual Reno BioResearch Product Faire Front Line event on June 3, 2013. Biotechnology Calendar hosts trade shows at top research institutions across the nation, and attracts purchasing agents, professors, and lab managers from research institutions and universities. See our full 2013 Nationwide Show Schedule for all other locations.

If you are interesting in finding out more information on funding stats and vendor info for the University of Nevada, Reno, feel free to click the button below:

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Comments

Dear Mrs./Mr. Professor, 
 
With your permission, we suggest a research topic 
related to mental illness. If there are no notable 
morphopatological changes between normal brain affect and 
create ill with schizophrenia, however, the schizophrenics 
were found excessive copper deposits in the central nucleus, which led to the idea of ​​ treating schizophrenia with Cuprenil 
(Penicillamin). Since Monoaminoxidase 
(MAO) is activated by copper, the idea is to remember and experimentally verified. 
SCHIZOPHRENIA MAY BE 
TREATED WITH PSYHODISLEPTICS ?  
It would be interesting to 
research what to induce delirium in patient with 
schizophrenia, are needed dose of LSD several times higher than the normal man !! 
"Copper role in metabolism." Cytochrome-oxidase structure has two atoms of copper. It is known that in conditions of acidosis (oxidative potential), the principle electronegativity metals, copper is removed from combinations of the Iron. So cytochrome oxidase will contain two atoms of iron instead of copper atoms, which changes its oxidation-reduction potential, but (most important), and color. If the copper was green, the iron is red, which radically change its absorption spectrum, based on the principle of complementary colors. If neoplastic cells, because acidosis is overactive acid form of cytochrome oxidase (red with iron atoms), which will absorb the additional green energy hydrogen atom (exclusively), the production of H20 , so water will prevail, in Schizophrenia , neuronal intracellular alkaline environment, will promote the basic form of cytochrome oxidase (green with copper atoms), which will oxidize only carbon atoms, the energy absorption of red (complementary) and production of CO2, so the fire will prevail. Drawn from this theory interdependent relationship between water and fire, of hydrogen(H2O) and carbon(CO2) ,in a controlled relationship with oxygen (O2). Indeed, water quenched the fire, as fire is to drain the water, so that antagonistic relationship between these elements, which seems at first sight is one of interdependence for proper development of cellular metabolic processes. The balance between these two elements is maintained by strict control mechanisms. The strain, these mechanisms are exhausted, and imbalances occur that can not be controlled, favoring carcinogenesis. Excess water will extinguish fire , even all, drowning cellular structures, reducing cell function in a primordial form. Normality consists of alternating the two forms of cytochrome oxidase by successive passage of acid in the alkaline form, in terms of acid-basic balance maintained within normal limits. If neoplastic cell is dark continuously, in schizophrenic neuron is continuous light. "Chlorophyll and hemoglobin, pigments life, porphyrin structure, differ only by the green chlorophyll, due to the atom of magnesium, and red hemoglobin, due to iron atoms in the structure - PROOF OF ORIGIN COMMON LIFE". (HEILMEYER) We designed an experiment to prove that the final biological oxidation, in addition to its oxidation-reduction, with formation of H2O and CO2, there is a photochemical effect, by which energy is transferred from the H atom, or C, process is done selct, the colors, complementary colors on the basis of the structures involved are colored (red hemoglobin Fe, Mg chlorophyll green, blue ceruloplasmin Cu, Fe cytochrome oxidase red, green - blue with Cu etc.). The basic idea is that if life pigments (chlorophyll, hemoglobin, cytochromes), which provides energy metabolism of the cell, are colored, we can control their activities through chromotherapy, on the basis of complementary color and energy rebalance the body, with a figured X- body-colored- ray. "Duality of cytochrome-oxidase. Proliferation (growth) and Differentiation (maturation) cell." Cytochrome-oxidase is present in two forms, depending on the context of acid-base internal environment : 1.- Form acidic (acidosis), which contains two Iron atoms, will be red, will absorb the additional green energy of the hydrogen atom, derived from carbohydrates, with formation of H2O, metabolic context that will promote cell proliferation. 2.-Form alkaline (alkalosis), containing two copper atoms, will be green, will absorb the additional red energy of the carbon atom, derived from carbohydrates, with formation of CO2, metabolic context that will promote cell differentiation. Please make possible this experiment , under your auspices, because they are one and exceeds my abilities. Please get involved in identifying the green form of ferment of Warburg. Red form has identified himself. Cytochrome-oxidase structure has two atoms of copper. It is known that in conditions of acidosis (oxidative potential), the principle electronegativity metals, copper is removed from combinations of the Iron. So cytochrome oxidase will contain two atoms of iron instead of copper atoms, which changes its oxidation-reduction potential, but (most important), and color. If the copper was green, the iron is red, which radically change its absorption spectrum, based on the principle of complementary colors. Normality consists of alternating the two forms of cytochrome oxidase by successive passage of acid in the alkaline form, in terms of acid-basic balance maintained within normal limits.  
I SUGGEST TO YOU AN EXPERIMENT : 
TWO PLANTS, A RED LIGHT ONLY, IN BASIC MEDIUM, WITH ADDED COOPER, WILL GROW, FLOWER AND FRUIT WILL SHORT TIME, AND THE OTHER ONLY LIGHT GREEN , IN AN ACID MEDIUM, WITH ADDED COOPER CHELATOR (CUPRENIL) , WHICH GROWS THROUGHOUT WILL NOT GROW FLOWERS AND FRUIT WILL DO. 
 
CULTURE OF NEOPLASTIC TISSUE IN A GREEN CONTAINER OR IN A COLOURLESS CONTAINER, IRRADIATED WITH MONOCHROMATIC GREEN LIGHT, IN AN ALKALINE MEDIUM, WITH ADDED COOPER, WILL IN REGRESSION OF THE TISSUE CULTURE. 
 
CULTURE OF NEOPLASTIC TISSUE IN A RED CONTAINER, OR SINGLE IRRADIATED WITH RED LIGHT, IN AN ACID MEDIUM, WITH ADDED COOPER CHELATOR (CUPRENIL), WILL LEAD TO EXAGERATED AND ANARCHICAL MULTIPLICATION. Sincerely yours, Dr.Viorel Bungau
Posted @ Thursday, December 13, 2012 1:15 PM by Viorel Bungau
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