Conference - Cambridge, United Kingdom
Cell senescence is a stable arrest of proliferation initiated by a variety of molecular triggers, including activated oncogenes and excess rounds of cell division.In addition, senescent cells secrete a cocktail of inflammatory and stromal regulators (the senescence-associated secretory phenotype) that influences the behaviour of neighbouring cells, including immune cells. Compelling evidence now indicates that cell senescence is a potent tumour suppression mechanism. At the same time, senescence likely contributes to tissue and organismal ageing.
This exciting new conference will bring together senior and junior researchers investigating mechanisms of cell senescence, the impact of senescence on cancer and ageing and avenues to exploit senescence in cancer and disease therapies.
(Courtesy of mTOR favors senescence over quiescence in p53-arrested cells, via www.impactaging.com)
Cambridge, July 20, 2013 – July 23, 2013
Wellcome Trust Genome Campus, Cambridge, UK
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